# Mathematical Biology Seminar

### Laura Miller

UNC

#### Electromechanical Pumping in the Embryonic Tubular Heart

#### Wednesday, November 7, 2012, at 3:05pm

LCB 225

Recent advancements in computational fluid dynamics have enabled researchers to
efficiently explore problems that involve moving elastic boundaries immersed in fluids
for problems such as cardiac fluid dynamics, fish swimming, and the movement of bacteria.
These advances have also made modeling the interaction between a fluid and an
electromechanical model of an elastic organ feasible. The tubular hearts of some
ascidians and vertebrate embryos offers a relatively simple model organ for such a study.
Blood is driven through the heart by either peristaltic contractions or valveless suction
pumping through localized periodic contractions. Models considering only the
fluid-structure interaction aspects of these hearts are insufficient to resolve the actual
pumping mechanism. The electromechanical model presented here will integrate feedback
between the conduction of action potentials, the contraction of muscles, the movement of
tissues, and the resulting fluid motion.