Currently, I am
working with my advisor, Aaron
Fogelson, on modeling blood clot formation and termination in flow.
I also worked with Aaron
Fogelson and Laura
Miller
on mechanotransduction and flow through the endothelial surface
layer.
For more information on
current research projects, see my research page.
publications
Leiderman Gregg, K. and
A.L. Fogelson. Grow with the Flow: A Spatial-Temporal Model of Platelet
Deposition and Blood Coagulation Under Flow. Math. Med. Biol.
(submitted).
Leiderman, K., L.A.
Miller, and A.L. Fogelson. The Effect of Spatial Inhomogeneities on
Flow Through the Endothelial Surface Layer. J. Theor. Biol. 2008; May
21;252(2):313-25. Link
Leiderman, K. and S.L. Steinberg. High-resolution models of motion of
macromolecules in cell membranes. Math. Comput. Simulat. 2008; April
4;77(4):383-399.
Zhang J, Leiderman K,
Pfeiffer JR, Wilson BS, Oliver JM, Steinberg SL.
"Characterizing the topography of membrane receptors and signaling
molecules from spatial patterns obtained using nanometer-scale
electron-dense probes and electron microscopy".
Micron. 2006;37(1):14-34. Epub 2005 Jul 11. Review. PubMed.
Oliver JM, Pfeiffer JR,
Surviladze Z, Steinberg SL, Leiderman K,
Sanders ML, Wofsy C, Zhang J, Fan H, Andrews N, Bunge S, Boyle TJ,
Kotula P, Wilson BS. "Membrane receptor mapping: the membrane
topography of Fc(epsilon)RI signaling." Subcell Biochem. 2004;37:3-34.
Review. PubMed
Wilson BS, Steinberg SL, Leiderman K, Pfeiffer JR, Surviladze Z, Zhang
J, Samelson LE, Yang LH, Kotula PG, Oliver JM.
"Markers for detergent-resistant lipid rafts occupy distinct and
dynamic domains in native membranes."
Mol Biol Cell. 2004 Jun;15(6):2580-92. Epub 2004 Mar 19. PubMed