Mathematical Biology Seminar

Jennifer Young
Friday, October 21st, 2011
4:00pm in LCB 225
"A Poroelastic Model of Intestinal Edema"

Intestinal edema is a medical condition referring to the accumulation of excess fluid in the interstitium of the intestinal wall. To study this phenomenon, we developed a computational, poroelastic model of edema formation in the intestinal wall. The intestinal wall is a multi-layered material, whose individual layers have distinct mechanical properties and structure. Partial differential equations are used to describe the deformation, fluid volume changes, and pressure changes in the intestinal wall. The problem is solved using a discontinuous Galerkin finite element method. To validate the model, simulation results are compared to results from four experimental scenarios.