Mathematical Biology Seminar|
Friday, October 21st, 2011
4:00pm in LCB 225
"A Poroelastic Model of Intestinal Edema"
Intestinal edema is a medical condition referring to the accumulation
of excess fluid in the interstitium of the intestinal wall. To study this
phenomenon, we developed a computational, poroelastic model of edema formation in
the intestinal wall. The intestinal wall is a multi-layered material, whose
individual layers have distinct mechanical properties and structure. Partial
differential equations are used to describe the deformation, fluid volume
changes, and pressure changes in the intestinal wall. The problem is solved using
a discontinuous Galerkin finite element method. To validate the model, simulation
results are compared to results from four experimental scenarios.