Mathematical Biology Seminar

Kristen Kwan, Human Genetics, U of U
Wednesday, November 17, 2021
3:05pm on Zoom
Cellular and Molecular Dynamics Shaping the Vertebrate Eye

Abstract: Our work involves tissue morphogenesis and the formation of 3-dimensional form in the embryo: how cells organize themselves into precise and stereotyped structures that are crucial for function. Specifically, we study the formation of the vertebrate eye, using multidimensional imaging of live zebrafish embryos, computational tools for quantitative image analysis, and molecular genetics. In this talk, I will discuss some of our current work dissecting molecular pathways governing eye morphogenesis under normal conditions and in disease, and I will outline outstanding problems and questions for the future, especially related to the intrinsic and extrinsic forces that shape the eye. We are potentially interested in thinking about and collaborating on computational methods, especially machine learning or soft matter modeling approaches in living systems, to address these problems.