Mathematical Biology Seminar

Adam Hughes
Department of Biochemistry, University of Utah

Understanding Organelle Relationships During the Aging Process

Wednesday, November 11, 2015, at 3:05pm
LCB 219

Our lab uses budding yeast as a model system to identify mechanisms cells use to achieve organelle homeostasis, and to understand how failure to maintain organelle integrity contributes to aging and the development of age associated diseases. In this talk, I will briefly discuss the role of metabolic crosstalk between the lysosome and mitochondria in cellular aging, and outline our recent discovery of a pathway for the selective degradation of mitochondrial metabolite carriers in response to excess cellular nutrients.