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Mathematical Biology seminar
Steve Cox
Computational and Applied Mathematics, Rice University
"Eavesdropping on Synaptic Traffic"
Wednesday, March 3, 2004
3:05 pm LCB 225
Nerve cells communicate to one another across synapses. The receiver
encodes this message as a change in local, in space and time,
conductance. This change engenders a postsynaptic change in potential
that actively diffuses through the dendritic tree and eventually may
lead to the firing of a nervous impulse which may in turn lead to a
long term change in the aforementioned synaptic conductance. To
quantify this synaptic plasticity we propose a non invasive cocktail
of optical imaging via voltage sensitive dyes and numerical
determination of synapse location and conductance time course. In this
talk we will focus on the mathematical and numerical study of the
sideways Hodgkin-Huxley system that permits one to eavesdrop on
synapses.
For more information contact J. Keener, 1-6089
E-mail:
keener@math.utah.edu
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