Mathematical Biology seminar
Dan Coombs
Dept of Biology
University of British Columbia
"Virus competition at multiple scales"
November 2, 2005
3:05pm, LCB 215
Viruses compete and are subject to natural selection at multiple levels:
within-cell, within-host and within-population (of hosts). We looked at
how viruses can optimally exploit their hosts and how this behaviour may
influence the most successful strategy at the between-host, or
epidemiological level. I will present a fairly general way to consistently
combine models of disease process and disease spread with the goal of
understanding the net selection pressure on a model virus. The method is
illustrated using a popular model for HIV dynamics nested within a simple
epidemiological model. This is joint work with Mike Gilchrist (Tennessee).
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Mathematical Biology Program
Department of Mathematics
University of Utah
155 South 1400 East Room 233
Salt Lake City, UT 84112
rasmusse@math.utah.edu
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