Mathematical Biology Seminar
Miguel Dumett
Department of Mathematics, University of Southern California
Wednesday February 2, 2005
3:05pm in LCB 121
"Estimation of alcohol
concentration from skin measurements"
The human body is divided in several compartments to facilitate
the description of the transport of alcohol in the human body
from ingestion to elimination. Experimental measurements of
transdermal vapor alcohol concentration are used to estimate
alcohol concentration in the body using an inverse problem
approach. The adjoint method is used for the computation of the
least squares functional gradient. In particular, a model that
links blood alcohol concentration and transdermal vapor alcohol
is proposed and the parameters of the model are fitted using real
breathalyzer and a transdermal alcohol skin device data applied
to individuals in a hospital. The parameter values obtained are
used to predict the evolution of alcohol concentration for
patients in the field. Kalman filtering techniques can be used
to correct predictions in real time.
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Mathematical Biology Program
Department of Mathematics
University of Utah
155 South 1400 East Room 233
Salt Lake City, UT 84112
rasmusse@math.utah.edu
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