Departmental Colloquium 2011-2012

Thursdays, 4:15 PM, JWB 335



September 15:
Speaker: Chris Johnson , The Scientific Computing and Imaging Institute at the University of Utah
Title: Image-Based Biomedical Modeling, Simulation, and Visualization
Abstract: Increasingly, biomedical researchers need to build functional computer models from images (MRI, CT, EM, etc.). The "pipeline" for building such computer models includes image analysis (segmentation, registration, filtering), geometric modeling (surface and volume mesh generation), large-scale simulation (parallel computing, GPUs), large-scale visualization and evaluation (uncertainty, error). In my presentation, I will present research challenges and software tools for image-based biomedical modeling, simulation and visualization and discuss their application for solving important research and clinical problems in neuroscience, cardiology, and genetics.

October 27:
Speaker: Andrei Caldararu, University of Wisconsin, Madison
Title: The Pfaffian-Grassmannian derived equivalence
Abstract: String theory relates certain seemingly different manifolds through a relationship called mirror symmetry. Discovered about 25 years ago, this story is still very mysterious from a mathematical point of view. Despite the name, mirror symmetry is not entirely symmetric -- several distinct spaces can be mirrors to a given one. When this happens it is expected that certain invariants of these "double mirrors" match up. For a long time the only known examples of double mirrors arose through a simple construction called a flop, which led to the conjecture that this would be a general phenomenon. In joint work with Lev Borisov we constructed the first counterexample to this, which I shall present. Explicitly, I shall construct two Calabi-Yau threefolds which are not related by flops, but are derived equivalent, and therefore are expected to arise through a double mirror construction. The talk will be accessible to a wide audience, in particular to graduate students. There will even be several pictures!

November 17:
Speaker: Eitan Tadmor, University of Maryland
Title: A new model for self-organized dynamics: from particle to hydrodynamic descriptions
Abstract: Self-organized dynamics is driven by "rules of engagement", which describe how each agent interacts with its neighbors. They consist of long-term attraction, mid-range alignment and short-range repulsion. Many self-propelled models are driven by the balance between these three forces, which yield emerging structures of interest. Examples range from consensus of voters and traffic flows to the formation of flocks of birds or school of fish, tumor growth etc.
We introduce a new particle-based model, driven by self-alignment, which addresses several drawbacks of existing models for self-organized dynamics. The model is independent of the number of agents: only their geometry in phase space is involved. We will explain the emerging flocking behavior of the proposed model in the presence of non-symmetric interactions which decay sufficiently slow, and discuss the difficulties of tracing graph connectivity otherwise. The methodology is based on the new notion of active sets, which carries over from particle to kinetic and hydrodynamic descriptions, and we discuss the unconditional flocking at the level of hydrodynamic description.

December 8:
Speaker: Keith Conrad, University of Connecticut
Title: Why is the Riemann Hypothesis Important?
Abstract: All mathematicians have heard that the Riemann Hypothesis is a significant open problem, but why is it such a big deal?
One can name plenty of older unsolved problems in number theory that get far less publicity. We care about the Riemann Hypothesis because it is connected to a large number of significant questions. I will discuss the history, scope, and range of consequences of the Riemann Hypothesis, with the aim of convincing mathematicians outside number theory that it deserves to be counted as one of the most important unsolved problems in mathematics.

January 12: SPECIAL COLLOQUIUM
Speaker: Hailin Sang, Indiana University, Bloomington
Title: Autoregressive model selection with simultaneous sparse coefficient estimation
Abstract: In this talk we study a sparse coefficient estimation procedure for autoregressive (AR) models based on penalized conditional maximum likelihood. The penalized conditional maximum likelihood estimator (PCMLE) thus developed has the advantage of performing simultaneous coefficient estimation and model selection. Mild conditions are given on the penalty function and the innovation process, under which the PCMLE satisfies a strong consistency and oracle property, respectively. Two penalty functions, least absolute shrinkage and selection operator (LASSO) and smoothly clipped average deviation (SCAD), are considered as examples, and SCAD is shown to have better performances than LASSO. At the end, we provide a simulation study and an application of this method to a historical price data of the US Industrial Production Index for consumer goods, and the result is very promising.
This is a joint work with Yan Sun.

January 19: SPECIAL COLLOQUIUM
Speaker: Jon Chaika, Universtiy of Chicago
Title: Interval exchange transformations
Abstract: Interval exchange transformations are invertible, piecewise order preserving isometries of the unit interval with finitely many discontinuities. Starting from rotations of the circle, which they generalize, this talk will present their connections to flows on flat surfaces, rational billiards and symbolic coding. Recent results on diophantine approximation for interval exchange transformations will be presented.

January 26: SPECIAL COLLOQUIUM
Speaker: Hongxiao Zhu, Duke University
Title: Bayesian graphical models for multivariate functional data
Abstract: In a broad variety of application areas there is interest in inferring the dependence structure in multivariate functional data. For data in vector form, conditional independence relationships between variables can be inferred through allowing zeros in the precision matrix through a Gaussian graphical model. Bayesian methods can be used to allow unknown locations of zeros, with a hyper inverse-Wishart prior chosen for the covariance. We generalize these methods to define a new class of Gaussian process graphical models for multivariate functional data. We focus on models with decomposable graph structures with a single precision matrix encoding the conditional independence between the functions. We also discuss the more general class of non-decomposable graphs. Properties of the proposed process are considered, and two efficient Algorithms are developed for posterior computation relying on Markov chain Monte Carlo. The methods are evaluated through simulation studies and applied to Electroencephalography (EEG) data in neuroscience.

January 31: SPECIAL COLLOQUIUM
NOTE different day: Tuesday
Speaker: Marisa Eisenberg, Ohio State University
Title: Structural Identifiability Methods for Modeling Human Disease
Abstract: Connecting models with data to yield predictive results requires a variety of parameter estimation, identifiability, and uncertainty quantification techniques. Identifiability analysis addresses the question of whether it is possible to uniquely recover the model parameters from a given set of data. In this talk, I will discuss my recent work developing identifiability methods using tools from computational differential algebra and systems theory. I will also present some applications to problems in human disease, including cholera, thyroid hormone regulation, and cancer.

February 2:
Speaker: John Morgan, Stony Brook University
Title: Geometrization of 3-manifolds
Abstract: The Geometrization Conjecture for 3-manifolds was formulated by Thurston in the early 1980s. `Geometric' manifolds are defined to be smooth manifolds that admit complete, finite-volume locally homogeneous Riemannian metrics. Such manifolds are local homogeneous spaces and thus can be enumerated in terms of Lie groups and finite co-volume lattices in them. Thurston's geometrization conjecture states that every compact 3-manifold is constructed from geometric ones by simple geometric operations. This conjecture is a vast generalization of the Poincare Conjecture, which can be reformulated as saying that every closed, simply connected 3-manifold is geometric, which means that it has a round (constant positive curvature) metric. Such a manifold is easily seen to be homeomorphic to the 3-sphere.
Perelman used Ricci flow techniques to study 3-manifolds and to prove the geometrization conjecture. There are two completely separate parts of the argument: Ricci flow with surgery deforms the metric and does connected sum decompositions. Eventually (i.e., for sufficiently large time) under this flow the metric on a 3-manifold becomes one that decomposes into 2 pieces: one piece on which the metric is converging smoothly to a complete hyperbolic metric and another piece on which the metric is locally volume-collapsed on a scale set by the negative part of the Riemannian curvature. These pieces are connected via incompressible tori. All of this is analytic/geometric relying on deep estimates about Ricci flow. To complete the proof of the geometrization conjecture, one must deal with the piece of the second type -- the locally volume-collapsed piece. For that one uses a wider class of spaces on which curvature bounded below makes sense, the so-called Alexandrov spaces. The local Alexandrov limits of the locally volume-collapsed piece are Alexandrov balls of dimension 1 or 2 and are completely understood.
From this one constructs nice local models which mesh well on the overlaps and from these one can show that the second piece is a disjoint union of pieces that fiber (including Seifert fiber) over one- and two-dimensional manifolds, completing the proof of the Geometrization Conjecture
In this talk we will describe the precise statement of the Geometrization Conjecture, briefly summarize how Ricci flow on a 3-manifold behaves as time goes to infinity. We then pass to a description of the locally volume-collapsed pieces in terms of their weak geometric limits and show how this is enough information to determine the topological type of the collapsing piece of the manifold.

February 3: SPECIAL COLLOQUIUM
NOTE different day and time: Friday, 4pm
Speaker: Dongbin Xiu, Purdue University
Title: A Flexible Stochastic Collocation Algorithm on Arbitrary Nodes via Interpolation
Abstract: Stochastic collocation method have become the dominating methods for uncertainty quantication and stochastic computing of large and complex systems. Though the idea has been explored in the past, its popularity is largely due to the recent advance of employing high-order nodes such as sparse grids. These nodes allow one to conduct UQ simulations with high accuracy and efficiency.
The critical issue is, without any doubt, the standing challenge of "curse-of-dimensionality". For practical systems with large number of random inputs, the number of nodes for stochastic collocation method can grow fast and render the method computationally prohibitive. Such kind of growth is especially severe when the nodal construction is structured, e.g., tensor grids, sparse grids, etc. One way to alleviate the difficulty is to employ adaptive approach, where the nodes are added only in the region that is needed. To this end, it is highly desirable to design stochastic collocation methods that work with arbitrary number of nodes on arbitrary locations. Another strong motivation is the practical restriction one may face. In many cases one can not conduct simulations at the desired nodes.
In this work we present an algorithm that allows one to construct high-order polynomial responses based on stochastic collocation on arbitrary nodes. The method is based on constructing a "correct" polynomial space so that multi-dimensional polynomial interpolation can be constructed for any data. We present its rigorous mathematical framework, its practical implementation details, and its applications in high dimensions.

February 7: SPECIAL COLLOQUIUM
NOTE different day: Tuesday
Speaker: Justin Kao, Massachusetts Institute of Technology
Title: Modeling the dynamics of fluid boundaries
Abstract: Fluid flows with free boundaries present the challenges of highly nonlinear dynamics, multiple scales, and complex physics due to interfaces between two substances. I examine some approaches to describing and understanding the behavior of these fluid boundaries, and discuss work on the rupture of thin liquid films, the evolution of wave-generated sand ripples, and other examples.

February 9:
Speaker: Eric Opdam, University of Amsterdam, Netherlands
Title: Harmonic analysis on p-adic reductive groups and homological algebra
Abstract: The Fourier decomposition of an L^2-function on a p-adic semi simple group G contains contributions from spectral series of various dimensions. These spectral series consist of irreducible representations of G which have "moderate growth behavior at infinity'', the so-called tempered irreducible representations. These tempered irreducible representations are therefore the relevant representations of G to consider when studying the harmonic analysis on G.
Tempered representations also have striking algebraic properties. With Maarten Solleveld we have proved an explicit formula for the space of higher extensions between irreducible tempered representations. This has applications to the computation of the so-called elliptic pairing of admissible characters of G (the so-called "Kazhdan orthogonality conjecture'').
With Dan Ciubotaru and Peter Trapa we considered an explicit construction of the (limits of) discrete series as the index of a Dirac operator (for graded affine Hecke algebras). This gives an expression of the aforementioned elliptic pairing in terms of index theory.

February 16: SPECIAL COLLOQUIUM
Speaker: Jianfeng Lu, New York University
Title: Multiscale analysis of solid materials: From electronic structure models to continuum theories
Abstract: Modern material sciences focus on studies on the microscopic scale. This calls for mathematical understanding of electronic structure and atomistic models, and also their connections to continuum theories. In this talk, we will discuss some recent works where we develop and generalize ideas and tools from mathematical analysis of continuum theories to these microscopic models. We will focus on macroscopic limit and microstructure pattern formation of electronic structure models.

February 23:
Speaker: Kay Magaard, University of Birmingham, England
Title: Generating Systems for Finite Groups with a View towards Geometry
Abstract: When, back in 1832, Galois proved that it is impossible to solve the general quintic by radicals he invented group theory and modern algebra. Crucial to Galois proof was the knowledge that a certain pair of permutations of degree 5 forms a generating set for S_5, the symmetric group of degree 5. For this he needed to discover the maximal subgroups of S_5, and was thus lead to two fundamental problems of group theory.
I will show how the classification of the finite simple groups provides new insight into both the maximal subgroup problem and the generation problem for finite groups and how this serves as a catalyst for ongoing developments in the theory of algebraic curves and surfaces.

March 1:
Speaker: Jeremy Quastel, University of Toronto, Canada
Title: The Kardar-Parisi-Zhang equation and its universality class
Abstract: The KPZ equation was introduced in 1986, and has become the default model in physics for random interface growth. It is a member of a large universality class with non-standard fluctuations, including directed random polymers. Even in one dimension, it turned out to be difficult to interpret and analyze mathematically, but at the same time to have a large degree of exact solvability. We will survey the history and recent progress.

March 8:
Speaker: Chris Jones, University of North Carolina
Title: What are Theory and Experiment in Climate Science? And Where’s the Math?
Abstract:Mathematicians have not been as involved in climate research as they are in many other areas of physics or biology, even compared with other areas of the geosciences. I will discuss how we may view climate research in way that makes the potential for our contributions clearer. I will also discuss some of the mathematical progress that will be needed to make advances in climate prediction, particularly in reference to the melding of data with computational models.

March 20:
NOTE different day: Tuesday
Speaker: Andrea Bertozzi, University of California Los Angeles
Title: Particle Laden Flow - applications from the Gulf Oil Spill to Spiral Concentrators
Abstract: This talk is about the challenges in modeling particle laden flow in viscous liquids and some of their applications. Particle settling in liquid is a complex process in which long range interactions are important due to the incompressibility of the fluid. Hinderance in particle settling is well-known as are other multi-particle effects such as shear-induced migration. We look at the basic physics of particle laden flow on an incline and show that this problem has a natural bifurcation between settling-dominated dynamics and dynamics dominated by the shear flow. In both cases the presence of particles greatly changes the flow structure from that of a single clear fluid. We also present some recent work connecting this physics to the modeling of particle separation in a spiral separator - used in the mining industry for separating different densities and sizes of particles in a slurry.
Mathematical models include both systems of conservation laws (involving both classical and singular shock solutions) and flows with surface tension.

March 22:
Speaker: Heinz-Otto Peitgen , Fraunhofer MEVIS, University of Bremen, Germany
Title: Biophysical Modeling and Numerical Simulation of Radio-Frequency-Ablation of Liver Tumors
Abstract: Radio-Frequency-Ablation together with Microwave-Ablation and High-Intensity-Focused-Ultrasound-Ablation have become significant alternatives to open surgery on cancer lesions. This is in particular true for Radio-Frequency-Ablation on liver lesions, where we see a rapid world wide increase in these procedures over the last decade. Although these procedures are minimally invasive and even can be applied in situations where open surgery is not possible they leave several problems and risks. The most challenging of these is that vascular systems in the neighborhood can challenge a complete destruction of a lesion because of cooling effects, thus rendering such a procedure as useless. We will discuss a fairly complete mathematical analysis of these problems ranging from a fundamental biophysical modeling and numerical simulation, including several optimal control frameworks for optimizing the procedure and identification of patient specific parameters, to a clinically manageable software application that includes planning, validation and guidance of a Radio-Frequency-Ablation procedure. Challenges for the other ablation procedures will also be addressed.

April 10: Distinguished Lecture Series
NOTE different day: Tuesday
Speaker: Howard Masur, University of Chicago
Title: Billiards in polygons, and the SL(2,R) action on moduli spaces of translation surfaces
Abstract: An appealing example of a dynamical system is billiards in a polygon. The most studied examples are when the vertex angles are rational multiples of pi. By an unfolding procedure the billiard flow gives rise to a straight line flow on what is called a translation surface. It turns out that the dynamics of the flow on an individual surface is intimately related to the study of the orbit of the surface under the action of the group SL(2,R) on the moduli space of all translation surfaces.
I will survey some of the major developments in this subject.

April 12: CANCELLED
Speaker: Lisa Fauci, Tulane University
Title: Spiny disks, flexible fibers and waving rings: explorations in phytoplankton fluid dynamics
Abstract: Phytoplankton motion in the ocean, at the scale of individual cells, involves the interaction of passive and actuated elastic structures with a surrounding fluid - a common theme in biological fluid dynamics. We present recent modeling results that shed light on the active swimming of dinoflagellates, as well as the passive motion of diatoms in shear flows . These diatoms may form chains or bear spines. In addition to examining how the flexibility and geometry of the diatoms affect their rotational dynamics, we will discuss how laboratory experiments and computational simulations are being calibrated in an effort to characterize the elastic properties of different species of chain-forming diatoms.

April 19: 2:30-3:30pm LCB 219
NOTE different time and location: 2:30-3:30pm LCB 219
Speaker: Dejan Slepcev, Carnegie Mellon University
Title: Coarsening in energy-driven systems
Abstract: Many energy-driven systems exhibit coarsening behavior. Starting from an unstable state a system quickly equilibrates locally, while remaining globally far from the equilibrium. The pattern, that initially forms, slowly coarsens over time --- the characteristic length scales of its features grow. I will discuss examples of the coarsening behavior in models of phase segregation, thin liquid films, and grain-boundary networks. In particular, I will present applications of the approach by Kohn and Otto for obtaining rigorous upper bounds on the rate of coarsening. I will discuss some limitations of the approach and how they may be overcome.